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Matchups for Oct. 14, 2022 include:
- Centennial vs. Southeast Polk
- AC/GC vs. Van Meter
- Waukee Northwest vs. Ankeny
- Dowling Catholic vs. West Des Moines Valley
- Urbandale vs. Waukee
- Norwalk vs. Carlisle
- Indianola vs. Bondurant
- Algona vs. Ballard
- Knoxville vs. ADM
- Harlan vs. Creston
- North Mahaska vs. Madrid
- Ames vs. Des Moines Lincoln
- A-H-S-T-W, Avoca 52, St. Albert, Council Bluffs 10
- ADM, Adel 56, Knoxville 3
- AGWSR, Ackley 28, West Fork, Sheffield 6
- Alburnett 32, Columbus Community, Columbus Junction 31
- Ames 60, Des Moines, Lincoln 13
- Ankeny 31, Waukee Northwest 7
- Aplington-Parkersburg 50, East Marshall, LeGrand 0
- Assumption, Davenport 12, Vinton-Shellsburg 7
- Atlantic 55, Saydel 6
- Audubon 56, Woodbine 48
- B-G-M 73, Melcher-Dallas 0
- Ballard 35, Algona 19
- Baxter 82, Twin Cedars, Bussey 6
- Bedford 60, East Union, Afton 14
- Bellevue 20, Clayton Ridge, Guttenberg 14
- Benton Community 49, Maquoketa 7
- Bishop Garrigan 63, Northwood-Kensett 0
- Bondurant Farrar 28, Indianola 14
- Boone def. Perry, forfeit
- CAM, Anita 58, Boyer Valley, Dunlap 20
- Camanche 31, Tipton 13
- Carlisle 49, Norwalk 28
- Cascade,Western Dubuque 49, Postville 14
- Cedar Falls 10, Bettendorf 7
- Cedar Rapids Xavier 42, Newton 3
- Cedar Rapids, Washington 21, Oskaloosa 6
- Centerville 44, Central Lee, Donnellson 7
- Central Lyon 62, Okoboji, Milford 6
- Charles City 19, South Tama County, Tama 6
- Clarinda 52, Red Oak 7
- Clarksville 94, Riceville 14
- Clear Lake 35, New Hampton 28
- Clinton 49, Mount Pleasant 26
- Colo-NESCO 78, GMG, Garwin 22
- Columbus Catholic, Waterloo 35, Sumner-Fredericksburg 7
- Council Bluffs, Abraham Lincoln 10, Des Moines, East 6
- Decorah 45, Waterloo, East 6
- Denver 43, South Hardin 26
- Des Moines Christian def. Shenandoah, forfeit
- Dike-New Hartford 67, Central Springs 34
- Dowling Catholic, West Des Moines 35, Valley, West Des Moines 3
- Dubuque, Hempstead 27, Waterloo, West 13
- Earlham 42, Riverside, Oakland 14
- East Buchanan, Winthrop 69, South Winneshiek, Calmar 13
- East Mills 69, Stanton 8
- East Sac County 21, West Monona 16
- Easton Valley 62, Kee, Lansing 12
- Edgewood-Colesburg 36, Midland, Wyoming 30
- Exira/Elk Horn-Kimballton 51, Coon Rapids-Bayard 14
- Forest City 36, Garner-Hayfield-Ventura 0
- Fort Dodge 28, Denison-Schleswig 7
- Gehlen Catholic, Le Mars 44, Alta-Aurelia 14
- Gladbrook-Reinbeck 68, Collins-Maxwell 14
- Glenwood 69, Council Bluffs, Thomas Jefferson 7
- Greene County 54, Clarke, Osceola 8
- Grundy Center 42, North Tama, Traer 0
- Hampton-Dumont-CAL 28, Center Point-Urbana 27, OT
- Harlan 56, Creston-Orient-Macksburg 12
- Harris-Lake Park 68, North Iowa, Buffalo Center 6
- Hartley-Melvin-Sanborn 41, Akron-Westfield 8
- Hinton 26, South O'Brien, Paullina 6
- Hudson 20, Nashua-Plainfield 14
- Independence 21, West Delaware, Manchester 20
- Iowa City High 55, Davenport, West 6
- Iowa City Liberty High School 29, Burlington 28
- Iowa Falls-Alden 28, Chariton 7
- Iowa Valley, Marengo 36, Lone Tree 22
- Janesville 70, Dunkerton 26
- Johnston 28, Cedar Rapids, Kennedy 7
- Kingsley-Pierson 75, Siouxland Christian 34
- LeMars 38, Spencer 28
- Lenox 28, Fremont Mills, Tabor 2
- Lewis Central 41, Dallas Center-Grimes 0
- Linn-Mar, Marion 72, Davenport, Central 0
- Lisbon 34, Starmont 12
- Logan-Magnolia 48, Lawton-Bronson 13
- Lynnville-Sully 48, Belle Plaine 14
- MFL-Mar-Mac 61, Beckman, Dyersville 0
- MOC-Floyd Valley 28, Boyden-Hull/Rock Valley 0
- Madrid 49, North Mahaska, New Sharon 8
- Marcus-Meridian-Cleghorn/Remsen Union (MMCRU) 49, Sidney 6
- Marion 28, Mason City 7
- Martensdale-St. Marys 62, Seymour 42
- Mediapolis 55, Louisa-Muscatine 7
- Mid-Prairie, Wellman 42, Davis County, Bloomfield 6
- Montezuma 78, Woodward Academy 0
- Monticello 58, Northeast, Goose Lake 28
- Moravia 46, Murray 6
- Mormon Trail, Garden Grove 42, Grand View Christian 21
- Mount Ayr 33, Southwest Valley 14
- Mount Vernon 47, Central Clinton, DeWitt 0
- Nevada 16, Humboldt 8
- New London 72, H-L-V, Victor 14
- Newell-Fonda def. Ar-We-Va, Westside, forfeit
- Newman Catholic, Mason City 49, North Union 27
- North Fayette Valley 48, Oelwein 0
- North Linn, Troy Mills 48, Maquoketa Valley, Delhi 6
- North Polk, Alleman 28, Gilbert 0
- North Scott, Eldridge 49, Fort Madison 14
- OA-BCIG 30, Clarion-Goldfield-Dows 14
- Ogden 39, IKM-Manning 20
- Osage 28, Crestwood, Cresco 12
- Ottumwa 32, Des Moines, North 20
- PAC-LM 26, Estherville Lincoln Central 20
- PCM, Monroe 28, Roland-Story, Story City 13
- Panorama, Panora 36, Nodaway Valley 34
- Pekin 35, Highland, Riverside 8
- Pella 35, Clear Creek-Amana 2
- Pella Christian 48, Central Decatur, Leon 14
- Pleasant Valley 49, Dubuque, Senior 7
- Pleasantville 50, Eldon Cardinal 17
- Prairie, Cedar Rapids 49, Iowa City West 28
- Regina, Iowa City 26, Durant-Bennett 12
- Ridge View 28, Sibley-Ocheyedan 7
- Ruthven-Ayrshire 62, St. Edmond, Fort Dodge 35
- Saint Ansgar 54, Lake Mills 6
- Sergeant Bluff-Luton 45, Bishop Heelan Catholic, Sioux City 28
- Sigourney-Keota 69, Van Buren, Keosauqua 20
- Sioux Center 25, Carroll 0
- Sioux City, North 70, Sioux City, West 0
- Solon 51, Grinnell 7
- South Central Calhoun 56, Belmond-Klemme 12
- South Hamilton, Jewell 60, Eagle Grove 14
- Southeast Polk 42, Ankeny Centennial 16
- Southeast Warren, Liberty Center 67, Lamoni 24
- Spirit Lake 24, Southeast Valley 6
- St. Mary's, Remsen 61, Glidden-Ralston 6
- Treynor 23, MVAOCOU 0
- Tri-Center, Neola 40, Westwood, Sloan 29
- Tripoli 46, Springville 6
- Turkey Valley, Jackson Junction 73, West Central, Maynard 32
- Underwood 28, Kuemper Catholic, Carroll 20
- Unity Christian 30, Sheldon 8
- Van Meter 54, AC/GC 0
- WACO, Wayland 42, Tri-County, Thornburg 10
- Wahlert, Dubuque 71, Jesup 6
- Wapello 45, North Cedar, Stanwood 6
- Wapsie Valley, Fairbank 52, BCLUW, Conrad 6
- Washington 35, Fairfield 28
- Waukee 30, Urbandale 7
- Waukon 42, Union Community, LaPorte City 0
- Waverly-Shell Rock 35, Epworth, Western Dubuque 14
- Wayne, Corydon 33, Colfax-Mingo 22
- Webster City 55, Storm Lake 7
- West Bend-Mallard 57, River Valley, Correctionville 18
- West Branch 54, Wilton 7
- West Burlington/Notre Dame 24, Keokuk 7
- West Central Valley, Stuart 17, Interstate 35,Truro 13
- West Hancock, Britt 52, North Butler, Greene 0
- West Harrison, Mondamin 52, Griswold 16
- West Liberty 32, Anamosa 13
- West Lyon, Inwood 42, Cherokee, Washington 12
- West Marshall, State Center 47, Albia 0
- West Sioux 68, Sioux Central, Sioux Rapids 0
- Western Christian 43, Emmetsburg 10
- Williamsburg 76, Eddyville-Blakesburg-Fremont 21
- Winfield-Mount Union 71, English Valleys, North English 8
- Winterset 30, Des Moines, Hoover 0
- Woodbury Central, Moville 56, Missouri Valley 14
- Woodward-Granger 55, Manson Northwest Webster 6